Although, In spite off, even though, ...
1.- A pesar de que Ana no pueda ir, no lo siente demasiado.
Although/Eventhough Ana can´t go she isn´t to sorry
in spite of not being able to go Ana, isn´t too sorry
2.- Ana no puede ir; sin embargo no lo siente demasiado.
Ana can´t go, however she isn´t too sorry.
3.- A pesar de los buenos consejos del médico no mejoré.
In spite of the doctor´s good advice, I din´t get better a piece of advice.
Although, the doctor gave me some good advice, I didn´t came better.
4.- Peter en realidad no necesitaba otra secretaria, y sin embargo cogió a una.
In fact Peter didn´t need another secretart, he took one, however.
5.- A pesar de haber dejado caer su reloj, John no le lo llevó al relojero.
Although he had dropped his watch,John didn´t take it to the watch-repairer´s.
6.- A pesar de que trabajó muchísimo el año pasado, Jim no ganó mucho dinero.
Althought he worked very hard last year, Jim didn´t earn much money.
7.- Mary lavó la camisa dos veces; sin embargo la mancha no quería salir.
Mary washed the shirt twice; however, the starm wouldn´t come out